主管：中华人民共和国司法部
主办：司法鉴定科学研究院
ISSN 1671-2072  CN 31-1863/N
中国司法鉴定

›› 2010 ›› Issue (1): 58-62.

• 论文 • 上一篇    下一篇

X-STR基因座的法医学应用研究进展

曾祥培;李海霞;孙宏钰;   

  1. 中山大学中山医学院法医物证教研室;
  • 出版日期:2010-01-15

The Research Progress of X Chromosome STR Loci in Forensic Genetics

ZENG Xiang-pei,LI Hai-xia,SUN Hong-yu (Department of Forensic Medicine,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510089,China)   

  • Published:2010-01-15

摘要： 对X染色体的结构特征、遗传特征及其短串联重复序列(STR)基因座在法医学领域的研究历史、现状进行了综述。并分析了X染色体STR基因座在混合斑鉴定和复杂亲子关系鉴定中的应用,以及在法医学领域应用中应注意的问题,如单倍型和连锁不平衡现象等。

关键词: 法医遗传学, X染色体, 短串联重复序列

Abstract: This article summarizes the structure and hereditary characteristics of X chromosome and the history and present situation of X-chromosome specific short tandem repeat (X-STR) loci in forensic medicine. The application of X-STR loci in mixed stain identification and complex paternity cases is discussed. Some problems which should been paid attention to when using X -chromosome STR loci in forensic medicine are also proposed,such as the haplotyping and linkage disequilibrium phenomena.

Key words: forensic genetics, X chromosome, short tandem repeat (STR)