主管：中华人民共和国司法部
主办：司法鉴定科学研究院
ISSN 1671-2072  CN 31-1863/N
中国司法鉴定

›› 2013 ›› Issue (3): 0-0.

• 鉴定实践 •    下一篇

同卵双生子甄别策略探讨

王彦学   

  1. 辽宁警官高等专科学校
  • 收稿日期:2012-11-21 修回日期:2013-01-31 出版日期:2013-05-15 发布日期:2013-06-04
  • 通讯作者: 王彦学

On the Strategies for Discriminating Monozygotic Twins

  1. Police academy of Liaoning
  • Received:2012-11-21 Revised:2013-01-31 Published:2013-05-15 Online:2013-06-04

被引次数

1

摘要： 同卵双生子（MZ）之间存在抗体库差异、甲基化修饰差异和基因突变体差异，甲基化修饰差异的比较可望成为甄别MZ的手段之一，抗体库差异和基因突变体差异比较的方法在甄别MZ方面亦有潜在价值。当前，对MZ的表观遗传以及基因突变等领域的研究还很有限，而抗体库技术的应用方法也有待探讨，因此MZ识别技术的应用前景和发展空间需要进一步摸索与完善。

关键词: font-size: 10.5pt, mso-bidi-font-size: 10.0pt, mso-ascii-font-family: 'Times New Roman', mso-hansi-font-family: 'Times New Roman', mso-bidi-font-family: 'Times New Roman', mso-font-kerning: 1.0pt, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA">同卵双生子；个体识别；抗体库；甲基化修饰；表观遗传学

Abstract: There are genetic differences in antibody library, methylation modification and gene mutants of monozygotic (MZ) twins. Analysis of methylation modification may be an applicable method for discriminating MZ twins. Comparisons of antibody library and gene mutants also have potential values. At present, the research and knowledge about MZ twins in epigenetics and related gene mutants is very limited. The technique of antibody library also needs to be improved. The application prospect and development of strategies of discriminating MZ twins need further exploration and improvement.