主管:中华人民共和国司法部
主办:司法鉴定科学研究院
ISSN 1671-2072  CN 31-1863/N

›› 2009 ›› Issue (04): 39-42+6.

• 论文 • 上一篇    下一篇

焦磷酸测序技术及其法医学应用

翟仙敦;刘之江;侯一平;   

  1. 四川大学华西基础医学与法医学院物证教研室;河南科技大学法医学院;浙江省宁波市公安局鄞州分局;

Pyrosequencing and Its Application in Forensic Science

ZHAI Xian-dun1,2, LIU Zhi-jiang3, HOU Yi-ping1(1.Department of Forensic Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China;2.Institute of Forensic Medicine, Henan University of Science and Technoogy,   

摘要: 焦磷酸测序技术是一类高通量、稳定、无需电泳、实时检测和定量的自动化测序技术,并广泛地应用于序列分析、遗传变异检测及定量分析的领域。对该技术的新进展及其在法医学和群体遗传学的应用作一综述。

关键词: 焦磷酸测序, 法医学应用

Abstract: Pyrosequencing method is a high throughout, stable, no gel electrophoresis, real-time detection and good quantitative method.It is widely used in the field of sequence analysis, mutation detection and quantitative analysis.In this paper, we re-viewed recent advances and discussed new applications of this technique in forensic science and population genetic areas.

Key words: pyrosequencing, forensic application