主管：中华人民共和国司法部
主办：司法鉴定科学研究院
ISSN 1671-2072  CN 31-1863/N
中国司法鉴定

中国司法鉴定 ›› 2021 ›› Issue (3): 36-44.DOI: 10.3969/j.issn.1671-2072.2021.03.004

• 鉴定综述 • 上一篇    下一篇

RNA在法医遗传学中的研究进展

张佳怡1，2，4，徐倩南2，3，陈丽琴1，赵珍敏2，刘希玲2   

  1. 1.内蒙古医科大学 法医学教研室，内蒙古 呼和浩特 010030； 2.司法鉴定科学研究院 上海市法医学重点实验室 上海市司法鉴定专业技术服务平台 司法部司法鉴定重点实验室，上海 200063；3.四川大学 华西基础医学与法医学院，四川 成都 610041； ４.南方医科大学 法医学院，广东 广州 510515

  • 收稿日期:2020-02-24 出版日期:2021-07-05 发布日期:2021-05-25
  • 作者简介:张佳怡（1994-），女，硕士研究生，主要从事法医遗传学研究。E-mail:2472509805@qq.com

RNA and Its Research Progress in Forensic Genetics

ZHANG Jiayi1,2,4, XU Qiannan2,3, CHEN Liqin1, ZHAO Zhenmin2, LIU Xiling2   

  1. 1. Department of Forensic Medicine, Inner Mongolia Medical University, Hohhot 010030 ,China;

    2. Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Senice Platform,

    Key Laboratory of Forensic Science Ministry of Justice, Academy of Forensic Science, Shanghai 200063, China;

    3. West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China；

    4. School of Forensic Medicine, Southern Medical University, Guangzhou 510515, China

  • Received:2020-02-24 Published:2021-07-05 Online:2021-05-25

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摘要：

DNA遗传标记在法医遗传学的应用及研究中一直占主导地位，随着分子生物学检测技术的发展，DNA甲基化和RNA等越来越多类型的遗传标记被应用于法医遗传学研究中。RNA作为个体遗传信息表达必不可少的重要桥梁，由于其本身具有组织特异性和时序性等多种特性，使其拥有独特的应用价值。近年来，众多学者尝试将其应用于法医学研究的诸多领域中，如死亡时间、死亡原因、创口形成时间、斑痕形成时间的推测以及体液来源和年龄推断等。为了更加详尽的探讨RNA在法医遗传学中的应用价值，通过对RNA在法医遗传学中的近期研究和应用进行了综述，以其在研究法医学领域中提供参考价值。

关键词:

法医遗传学, RNA, 体液识别, 组织特异性, 年龄推断

Abstract:

DNA genetic markers have been playing a leading role in the application and research of forensic genetics. With the development of molecular biology detection technologies, more and more genetic markers, such as DNA methylation and RNA, can be applied in forensic genetics. As an indispensable bridge for expression of individual genetic information, RNA has its unique application value due to its various characteristics such as tissue specificity and time specificity. In recent years, many scientists tried to apply it to many fields of forensic research, which can be used for inferring death time, cause of death, wound formation time, speculation of scar formation time, and body fluid source and age inference, etc. In order to further explore the application value of RNA in forensic genetics, we will review the recent research and application of RNA in forensic genetics.

Key words:

forensic genetics, RNA, body fluid identification, tissue specificity, age estimation

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