Abstract:

Forensic toxicology concerns the analysis of biological specimens for the presence of drugs and poisons to determine what role the detected substances play in death or impairment of human performance. The interpretation of the results is the ultimate purpose of forensic toxicology. Modern forensic toxicology consists of three major areas： post-mortem forensic toxicology， forensic urine drug testing， human-performance forensic toxicology. This article discusses various factors that enter into the interpretation process in each area. The results must be interpreted with caution. Apart from the measured concentrations， many affecting factors like data from autopsy and investigation， drug toxicity， types of biosamples， pharmacokinetics， redistribution， and drug interactions should be taken into full consideration so that accurate result interpretations could be achived in cases.

Key words: interpretation of results, forensic toxicology, factor, drug and poison, pharmacokinetics, redistribution

摘要：

法医毒理学的主要任务是从生物检材中分析毒（药）物，并且推断毒（药）物浓度对死亡或行为能力的作用程度，结果解释是法医毒理学的最终目的。现代法医毒理学主要包括死后法医毒理学、滥用药物筛查和行为能力影响三个方面，由此探讨在进行结果解释时的诸多影响因素。进行法医毒理学的结果解释时应非常慎重，充分了解案情和调查结果，充分考虑毒（药）物的毒性、生物检材、药代动力学、体内再分布、药物交叉反应等多种因素，才能对案件作出较为准确的结果解释。

关键词: 结果解释, 法医毒理学, 影响因素, 毒（药）物, 药代动力学, 体内再分布