Abstract:

Objective To establish a method for the analysis of organic solvent residues in solid heroin by HS-GC/FID and HS-GC/MS. Methods Forty two samples which had been treated with dry or wet method， were sealed， then heated and shaken at 90℃ for 20 min. The headspace gas was detected by GC/FID （DB-WAX， 30 m × 0.25 mm × 0.25 μm） and GC/MS （HP-5 MS， 30 m × 0.25 mm× 0.25 μm）. The qualitative analysis was performed with the help of 17 known solvents references used as external standards. The quantitative analysis of 5 mutual solvents was performed by adding water to the samples and measuring the corresponding peak height. Results Twelve organic solvents were found in 42 samples， e.g. acetic acid， diethyl ether， ethanol， ethyl acetate， acetaldehyde， chloroform， etc. The relative amount of 5 mutual residual solvents in those samples was different from one another. Conclusion This method is rapid， convenient and reliable. The analysis results of 42 samples could be informative in the heroin source and lots investigation.

Key words: forensic science, heroin, chromotography, gas, gas chromotography-mass spectrometry, organic solvent residues

摘要：

目的 建立固体海洛因毒品中残留有机溶剂的顶空-气相色谱和顶空-气相色谱-质谱联用检测方法。方法 采用干法和湿法处理42份样品，密封后90 ℃加热振荡20 min，抽取顶空气体用气相色谱法（DB-WAX毛细柱，30 m × 0.25 mm，0.25 μm）和气相色谱-质谱联用法（HP-5MS毛细柱，30 m × 0.25 mm，0.25 μm）检测，以已知17种有机溶剂外标法定性。在样品中加水后检测，根据峰高估算5种共有成分的含量。结果 在42份海洛因毒品中检出乙酸、乙醚、乙醇、乙酸乙酯、乙醛、三氯甲烷等12种有机溶剂成分，5种主要共有成分相对含量有差别。结论 本研究建立的检测方法快速、简便，定性可靠，可用于固体海洛因毒品的来源与批次分析。

关键词: 法庭科学, 海洛因, 色谱法, 气相, 气相色谱-质谱法, 残留有机溶剂