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Research Progress of New Psychoactive Substances of Phenethylamines
ZHOU Liying
2020(6):
17-27.
DOI: 10.3969/j.issn.1671-2072.2020.06.003
New psychoactive substances of phenethylamines are a class of compounds with dual psychoactive effects of hallucinations and excitement. It uses phenethylamine as the mother nucleus, and through the chemical structure modification to synthesize phenethylamine derivatives to circumvent the laws and regulations of various countries. Its pharmacological effects are similar to traditional drugs, and even more toxic. Abuse of phenethylamines can cause symptoms such as nausea, vomiting, tachycardia, hypertension, respiratory depression, and hallucinations, and even severe limb ischemia, liver and kidney failure and death, which seriously affects human physical and mental health and public safety. New psychoactive substances of phenethylamines have drawn great attention from the international community, and the study of their pharmacological and toxicology and analysis methods has become a research hotspot in the field of forensic toxicology analysis. This article reviews the in vivo processes, sample preparation, and analysis methods of new psychoactive substances of phenethylamine, in order to provide a basis for the practice of forensic identification.
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