主管：中华人民共和国司法部
主办：司法鉴定科学研究院
ISSN 1671-2072  CN 31-1863/N
Chinese Journal of Forensic Sciences

Chinese Journal of Forensic Sciences ›› 2022 ›› Issue (2): 41-45.DOI: 10.3969/j.issn.1671-2072.2022.02.06

• Forensic Science • Previous Articles     Next Articles

Rapid Identification of Novel Synthetic Cannabinoid 5F-EDMB-PICA by Mass Spectrometry

YUAN Min1, WANG Xuehu2，YUAN Zhiwei1，et al   

  1. 1. Nanjing Customs District Industrial Products Inspection Center, Nanjing, 210019; 2. Institute of Forensic Science, Jiangsu Provincial Public Security Bureau, Nanjing 210024, China; 3. Institute of Forensic Science of Public Security Bureau of Nanjing City, Nanjing, 210015； 4. SCIEX Analytial Instrument Trading Co., Shanghai 200335, China；
    5. Shimadzu（China）Co., LTD., Shanghai 200000, China
  • Received:2021-06-10 Published:2022-03-15 Online:2022-04-26

基于质谱快速确认新型合成大麻素5F-EDMB-PICA

袁 敏1，王学虎2，袁智伟1，等   

  1. 1.南京海关工业产品检测中心，南京 210019； 2.江苏省公安厅物证鉴定中心，南京 210024；
    3.南京市公安局禁毒支队毒品检验室，南京 210015；4.上海爱博才思分析仪器贸易有限公司，上海 200335；
    5.岛津企业管理（中国）有限公司上海分公司，上海 200000
  • 通讯作者: 王学虎（1977—），男，高级工程师，主要从事法医毒物和毒品分析研究工作。E-mail:wxh771229@aliyun.com
  • 作者简介:袁敏（1978—），女，高级工程师，博士，主要从事涂料、木制品、矿产品、纺织原料、海关查缉样品等检验工作。E-mail：270851708@qq.com

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Abstract:

Objective A method for identifying the molecular structure of synthetic cannabinoids （5F-EBMD-PICA） was established. Methods According to the GC-MS and the search of the Spectral Library, the molecular formula derived from the LC-Q-TOF-MS first-order mass spectrum of the known substance 5F-MBMD-PICA was compared and analyzed, the new structure of synthetic cannabinoids in the sample cut tobacco was obtained and verified by consulting the literature. Results A sample of cut tobacco seized by customs was determined to contain 5F-EBMD-PICA. Conclusion This method can provide a new way to resolve the structure of unknown synthetic cannabinoids.

Key words:

synthetic , cannabinoid,  , GC-MS,  , LC-Q-TOF-MS,  , 5F-MDMB-PICA,  , 5F-EDMB-PICA

摘要：

目的 构建一种识别合成大麻素5F-EDMB-PICA分子结构的方法。方法 根据气相色谱-质谱法（GC-MS）以及谱库检索提示，对比已知物5F-MDMB-PICA的气质质谱碎片归属解析，结合液相色谱-四级杆-飞行时间质谱法（LC-Q-TOF-MS）的一级质谱拟合的分子式，推导出缴获样品烟丝内的新型合成大麻素结构，并通过文献资料得到验证。结果 对一例海关查获样品烟丝进行了检验，判定其中含有合成大麻素成分5F-EDMB-PICA。结论 该方法可为解析未知合成大麻素的分子结构提供新途径。

关键词:

合成大麻素；气相色谱-质谱法；液相色谱-四级杆-飞行时间质谱法；5F-MDMB-PICA；5F-EDMB-PICA ,

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